Dr. Fitness and the Fat Guy Weight Loss Radio

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Friday, October 27, 2006

Why Oprah and Nicole Ritchie Will Be Listening!!!!

Tune in Sunday night to "Dr. Fitness and the Fat Guy" from 7 - 8 PM EDT!!! We have the lovely, Lisa Lillien, "The Hungry Girl," Hungry-girl.com, one of the best web sites on the entire web talking about Halloween Tricks or Treats. We also have Oprah Magazine's Top Trainer, Michael Gonzalez-Wallace, talking about his new awesome exercise DVD Series, and his workoutout can be found at www.sportstrengthtraining.com. If that wasn't enough, we have the beautiful "Nutrition Twins," Tammy and Lyssie Lakatos Nutritiontwins.com giving us the skinny on Halloween candy and what Nicole Ritchie is going to do about gaining weight.

Thursday, October 05, 2006

Scientists Use Gene Therapy to Fight Advanced Cancer

Dr. Fitness found this great info on the search to cure cancer!!!!
Government scientists turned regular blood cells into tumor attackers that wiped out all signs of cancer in two men with advanced melanoma. The striking finding, unveiled Thursday, marks an important step in the quest for gene therapy for cancer.
But the genetically altered cells didn't help 15 other melanoma victims. So scientists are trying to strengthen the shots.
Still, the National Cancer Institute called its experiment the first real success in cancer gene therapy - because it fought cancer's worst stage, when it has spread through the body, unlike earlier attempts that targeted single tumors.
And the government hopes to soon begin testing the gene therapy in small numbers of patients dying from more common cancers, such as advanced breast or colon cancer.
The hope is that one day, such treatment might provide long-lasting tumor suppression.
"It's not like chemotherapy or radiation, where as soon as you're done, you're done," said lead researcher Dr. Steven Rosenberg, the NCI's surgery chief. "We're giving living cells which continue to grow and function in the body."
The first two successful patients appear melanoma-free almost two years after infusions of tumor fighters made from their own blood. Doctors can't predict how the men will fare long-term. Melanoma, the most aggressive skin cancer and killer of almost 8,000 Americans a year, is notorious for returning years after patients think they've subdued it.
"I'm cured for now," is how a grateful Mark Origer, 53, of Watertown, Wis., put it after a checkup from NCI doctors this week. "I know how fortunate I am to have gone through this and responded to this. Not everybody's that lucky."
Cancer specialists praised the work, published Thursday by the journal Science, but warned that years of additional research are needed.
"Clearly this is a first step," cautioned Dr. Len Lichtenfeld of the American Cancer Society. "We have to be very cautious about not raising hopes too much."
But, "it is exciting," he added. "It certainly is a proof of concept that this approach will work."
NCI's Rosenberg has long led a tantalizing research field: how to harness the body's immune system to fight cancer. White blood cells called T-lymphocytes hunt down germs and other foreign tissue. But cancerous cells look a lot like healthy cells, making it hard for those T-cells to spot a problem.
By 2002, Rosenberg had made a breakthrough. He found small numbers of cancer-fighting T-cells inside some patients with advanced melanoma. He literally pulled those cells out of their blood, and grew billions more of them in laboratory dishes, enough to have a chance at overwhelming a tumor when they're pumped back into patients. About half significantly improve after this so-called "cell-transfer therapy."
But few melanoma patients make enough cancer-fighting T-cells naturally for scientists to spot in their bloodstream, and T-cells that attack other cancers are virtually impossible to find. So Rosenberg and colleagues set out to create those tumor fighters from scratch.
The scientists took normal lymphocytes - ones that don't recognize cancer - out of 17 patients with advanced melanoma who had exhausted their treatment options. They infected those cells with a virus carrying genes that create T-cell receptors, essentially homing devices for, in this case, melanoma. (Different genes create receptors for other cancers.)
"We can take a normal cell from you or me or any patient and ... convert that cell into a cell that recognizes the cancer," Rosenberg explained.
In 15 of the 17 patients who tried it, the newly armed cells took root and grew at low levels for a few months. But only two saw their tumors gradually fade away - Origer and a 30-year-old whose T-cell levels remained super-high for over a year.
Why did the genetically altered cells flourish in only two people?
"That's the critical question," said Dr. Patrick Hwu, melanoma chairman at the University of Texas M.D. Anderson Cancer Center, who once worked with the NCI team.
Picking the right lymphocyte to genetically alter isn't easy - there are many different kinds - or perhaps more precise T-cell receptors were needed, Hwu suggested.
But "these are all solvable issues," he stressed, calling the study "one of the first documented, effective cases of cancer gene therapy working." Dr. Fitness wants everyone to keep their fingers crossed!!!

Dr. Fitness Recommendations For Fibromyalgia

If you have a close friend or family member who has been dealing with the condition known as Fibromyalgia, you know how debilitating it could be. I recently talked about the condition on one of our previous shows but I wanted to make sure our listeners who suffer from this or know someone with the condition can use this information as a resource.
Fibromyalgia is considered to be a syndrome—a set of symptoms that occur together but do not have a known cause. 3.7 million Americans have fibromyalgia, still a very poorly understood disorder characterized by widespread pain and tenderness, but also often associated with nervousness, fatigue, depression and insomnia. In addition, many will suffer from chemical sensitivities, allergies, irritable leg syndrome, irritable bowel syndrome, trigeminal neuralgia and a host of other symptoms. Women are far more likely to be diagnosed with the condition than men.
Fibromyalgia is different than most diseases in that it takes away the patients ability to fight.There are theories as to what may cause it, but there is not enough evidence to support any single theory. People—especially women—who have a family member with fibromyalgia are more likely to develop it themselves. It has been recognized as a medical disorder only since the 1980s.
Some theories suggest that fibromyalgia may be linked to:
•Oversensitive nerve cells in the spinal cord and brain. Oversensitivity may be due to changes in chemicals in the brain or spinal cord that regulate pain. As a result, the person senses pain more easily, and widespread muscle pain occurs.
•An imbalance in the brain chemicals that control mood, which results in a lowered tolerance for pain and may also cause an unrestful sleep cycle and fatigue. Once this occurs, a person becomes less physically active, and the muscles and tissues become more sensitive and painful and more easily irritated.
•An imbalance of hormones such as cortisol and growth hormone. Their release is controlled by the pituitary gland and the hypothalamus. Imbalances of these hormones can result in fatigue, mood changes, concentration and memory difficulties, a lowered tolerance for pain, and other symptoms.
•A disturbance in the deep phase of sleep. Some chemicals, such as growth hormone, are secreted by the body during this phase of sleep. If sleep is disrupted, the body produces less of the hormone. Disturbed sleep may be both a cause and an effect of the pain of fibromyalgia.
Many people connect the beginning of their fibromyalgia symptoms to a certain event. These events can include an illness such as the flu, an injury or surgery, or emotional trauma and stress. An event of this type combined with other factors, such as increased sensitivity to pain and an ongoing sleep disturbance, may lead to fibromyalgia syndrome in some people.

What Can You Do For Fibromyalgia?
First and foremost, it is imperative to get properly diagnosed and typically there is some underlying problem such as herniated discs or other injuries that may not have been identified and treated. Here is some of the typical treatments that are available. There are medicines to help you sleep better, relax muscles, or relieve muscle and joint pain. Medicines your doctor may suggest include tricyclic antidepressants, SSRIs Selective serotonin reuptake inhibitors (SSRIs) for fibromyalgia
citalopram hydrobromide (Celexa)
escitalopram oxalate (Lexapro)
fluoxetine hydrochloride (Prozac)
paroxetine hydrochloride (Paxil)
sertraline hydrochloride (Zoloft)

•Muscle relaxants such as cyclobenzaprine (Flexeril), anticonvulsants (also called antiepileptics), mixed (or dual) reuptake inhibitors or, less often, nonprescription pain relievers.
•Exercise therapy to relieve sore muscles and increase energy.
•Cognitive-behavioral therapy to help you learn to manage your pain.
•Chiropractic Manipulation
*Nutritional Supplementation and Dietary Modifications

All of these therapies have their place and should be used in some combination. I want you to also check out two fantastic website for even more info on proper supplementation and Chiropractic therapy. Dr. Paul Whitcomb's website www.stopfibro.com and Dr. Rodger Murphree's website www.treatingandbeating.com

Dr. Fitness and the Fat Guy Give a Double Thumbs Up For Beth Aldrich

We recently interviewed a wonderful guest named Beth Aldrich. She is the type of person that leaves such a positive lasting impression. She has a TV show called "For Her Information" that is on your local PBS Channel and definitely go to her website www.forherinformation.com to check out her show and sign up for her great newsletter!!! Her show focuses on how be a chic mother as well as trying to look after the environment and your health.